Activity-dependent neuroprotective protein

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Common Name:Activity-dependent neuroprotective protein
Other Names, such as IUPAC Name
Activity-dependent neuroprotector homeobox protein
Biochemical Information
Molecular Structure
Important Issues in Man
Relevant Clinical Literature
UK Guidance
Other Wikis
Wikipedia on Activity-dependent neuroprotective protein (Less technical, ? quality control)

Coded by the ADNP gene at 20q13.13 this is a 1102 amino acid peptide which seems to be a widely expressed transcription factor. Its expression is modulated by vasoactive intestinal peptide. It contains a 8 aminio acid neuroprotective sequence davunetide.

Deficiency in animal models results in neural tube closure defects and death in utero with strong association with neuronal cell differentiation and maturation.

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