A recombinant human alpha-galactosidase A. (see also Agalsidase alpha)
IV 1mg/kg body weight administered once every 2 weeks
IgG antibodies typically develop after 3 months. Immunologic tolerance can later develop.
Cautions and Interactions
At some stage almost 70% have some form of (mild) reaction
The mature glycosylated protein is composed of 2 subunits of 398 amino acids. Made in mammalian Chinese Hamster Ovary (CHO) cell culture.