Alfacalcidol

From Ganfyd

rINN: Alfacalcidol

Other Names

1α-hydroxycholcalciferol, AlphaD, Alphacalcidol, 1 alpha-hydroxycholecalciferol, One-Alpha^®

Pharmacological Information

Pharmacology Images

Alfacalcidol Molecule

Web information on Alfacalcidol

NHS Evidence on Alfacalcidol

DrugBank on Alfacalcidol

Mechanism of Action

pro-hormone

Relevant Clinical Literature

Pubmed on Alfacalcidol

RCT with Alfacalcidol

Systematic reviews of Alfacalcidol

Alfacalcidol in N Eng J Med, Lancet, JAMA, BMJ

Alfacalcidol in Cochrane Collaboration

TRIP Database on Alfacalcidol

Google Scholar on Alfacalcidol

Bandolier on Alfacalcidol

UK Guidance

SNOMED search

Nice Guidance on Alfacalcidol

BNF-registration required
BNF for children-registration required

UK directory of medicines

UK Medicine Guide (eg pictures of capsules)

Centre for Reviews and Dissemination databases -DARE & NHS EED (evaluates reliability of research)

Prodigy Guidance on Alfacalcidol

Regulatory Literature

UK SPCs of medicines with marketing authorisation

EMEA search

FDA search

Other Literature

PubChem on Alfacalcidol

CTD (Comparative Toxicogenomics Database) link

ChemIndustry.com link

Protein Structural Information

Biological Information (GenomeNet)

Protein Knowledgebase (UniProtKB)

Please read pharmacological data limitations

Other Wikis

Medpedia on Alfacalcidol (Less technical, good quality control)

Wikipedia on Alfacalcidol (Less technical, ? quality control)

Introduction

The active hydroxylation product of Vitamin D used for therapy in renal failure as remainder of hydroxylation not kidney dependent.

Clinical Use

Indications

Administration

Oral

Clinical Issues

Contra-indications

Cautions and Interactions

Side effects

Special advice

Pharmacology