Amiloride

From Ganfyd

rINN: Amiloride_Hydrochloride

Other Names

Amilamont^®

Pharmacological Information

Pharmacology Images

Amiloride Molecule

Web information on Amiloride_Hydrochloride

NHS Evidence on Amiloride_Hydrochloride

DrugBank on Amiloride_Hydrochloride

Mechanism of Action

retain potassium from distal tubule

Relevant Clinical Literature

Pubmed on Amiloride

RCT with Amiloride

Systematic reviews of Amiloride

Amiloride in N Eng J Med, Lancet, JAMA, BMJ

Amiloride in Cochrane Collaboration

TRIP Database on Amiloride

Google Scholar on Amiloride

Bandolier on Amiloride

UK Guidance

SNOMED search

Nice Guidance on Amiloride

BNF-registration required
BNF for children-registration required

UK directory of medicines

UK Medicine Guide (eg pictures of capsules)

Centre for Reviews and Dissemination databases -DARE & NHS EED (evaluates reliability of research)

Prodigy Guidance on Amiloride

Regulatory Literature

UK SPCs of medicines with marketing authorisation

EMEA search

FDA search

Other Literature

PubChem on Amiloride_Hydrochloride

CTD (Comparative Toxicogenomics Database) link

ChemIndustry.com link

Protein Structural Information

Biological Information (GenomeNet)

Protein Knowledgebase (UniProtKB)

Please read pharmacological data limitations

Other Wikis

Medpedia on Amiloride (Less technical, good quality control)

Wikipedia on Amiloride (Less technical, ? quality control)

Introduction

Clinical Use

Indications

• Potassium conservation
• Oedema

Administration

Oral

Clinical Issues

Contra-indications

• Renal failure

Cautions and Interactions

• Care with potassium suppliments, renal failure, angiotensin-II receptor agonists and ACE inhibitors with frequent monitoring of serum potassium if such combinations indicated

Side effects

• Hyperkalaemia

Special advice

Pharmacology