Angiokeratomas (purpura papulosa haemorrhagica Hebrae) are found in galactosialidosis such as alpha-galactosidase deficiency. They have also been described in Turner's syndrome. There is a systemic variety, called angiokeratoma corporis diffusum and rare forms such as angiokeratoma circumscriptum and angiokeratoma circumscriptum naeviforme (present at birth).
One or several dark red papules, mostly with a verrucous surface
Show ectasias of the papillary dermal blood vessels with secondary epidermal changes in the form of acanthosis and/or hyperkeratosis.
- Angiokeratoma of Mibelli
- Angiokeratoma of Fordyce
- Angiokeratoma corporis diffusum
- Lesions are usually symmetrically distributed and are mostly concentrated between the umbilicus and knees
- Commonest cause is alpha-galactosidase deficiency
- Angiokeratoma circumscriptum
- Solitary or multiple angiokeratomas, smaller than angiokeratoma circumscriptum
This article is a stub. Please feel free to expand it and make it more encyclopaedic.