Angiokeratoma
From Ganfyd
Web Resources for Angiokeratoma
Relevant Clinical Literature
UK Guidance
Other Wikis
Medpedia on Angiokeratoma (Less technical, good quality control)
Wikipedia on Angiokeratoma (Less technical, ? quality control)
Angiokeratomas (purpura papulosa haemorrhagica Hebrae) are found in galactosialidosis such as alpha-galactosidase deficiency. They have also been described in Turner's syndrome. There is a systemic variety, called angiokeratoma corporis diffusum and rare forms such as angiokeratoma circumscriptum and angiokeratoma circumscriptum naeviforme (present at birth).
Contents |
Appearance
One or several dark red papules, mostly with a verrucous surface
Pathology
Show ectasias of the papillary dermal blood vessels with secondary epidermal changes in the form of acanthosis and/or hyperkeratosis.
Classification
- Angiokeratoma of Mibelli
- Angiokeratoma of Fordyce
- Angiokeratoma corporis diffusum
- Lesions are usually symmetrically distributed and are mostly concentrated between the umbilicus and knees
- Commonest cause is alpha-galactosidase deficiency
- Angiokeratoma circumscriptum
- Solitary or multiple angiokeratomas, smaller than angiokeratoma circumscriptum
Picture links
- http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2704393/figure/F1/
- http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2883402/figure/F1/
- http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2883402/figure/F2/
This article is a stub. Please feel free to expand it and make it more encyclopaedic.
