Apolipoprotein A-V

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Apo-AV is processed from the 366 amino acid peptide coded by the APOA5 gene. It is related to plasma triglycerides and found mainly in HDL and to a lesser extent in VLDL. There are 3 common alleles:

  • APOA5*1
  • APOA5*2
  • APOA5*3

Defective production is associated with familial hypertriglyceridaemia and hyperlipoproteinaemia type V