Arvid Carisson

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Arvid Carisson (25/1/1923), a clinical pharmacologist, graduated in medicine from Lund University where he also discovered that dopamine was a neurotransmitter in the brain and first proposed in 1958 that levodopa was a potential treatment for Parkinsons disease. In fact just prior to this while in the USA he discovered in 1957 that DOPA reversed reserpine's neurotransmitter depletion affects and so the link to Parkinsonism was there to be made. He and his cowarkers also developed the first SSRI to market (zimelidine, later withdrawn), were the first to understand how major tranquillizers worked by depleting dopamine.