Basiliximab

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rINN: Basiliximab
Other Names
Simulect®
Pharmacological Information
Web information on Basiliximab
NHS Evidence on Basiliximab
DrugBank on Basiliximab
Mechanism of Action
Monoclonal antibody directed against the IL-2 receptor α-chain (CD25 antigen)
Relevant Clinical Literature
Pubmed on Basiliximab
RCT with Basiliximab
Systematic reviews of Basiliximab
Basiliximab in N Eng J Med, Lancet, JAMA, BMJ
Basiliximab in Cochrane Collaboration
TRIP Database on Basiliximab
Google Scholar on Basiliximab
Bandolier on Basiliximab
UK Guidance
Nice Guidance on Basiliximab

BNF-registration required
BNF for children-registration required

UK directory of medicines
UK Medicine Guide (eg pictures of capsules)
Centre for Reviews and Dissemination databases -DARE & NHS EED (evaluates reliability of research)
Prodigy Guidance on Basiliximab
Regulatory Literature
UK SPCs of medicines with marketing authorisation
EMEA search
FDA search
Other Literature
PubChem on Basiliximab
CTD (Comparative Toxicogenomics Database) link
ChemIndustry.com link
Protein Structural Information
Biological Information (GenomeNet)
Protein Knowledgebase (UniProtKB)
Please read pharmacological data limitations
Other Wikis
Medpedia on Basiliximab (Less technical, good quality control)
Wikipedia on Basiliximab (Less technical, ? quality control)

Basiliximab is used in organ transplantation and prevents binding of interleukin 2, the signal for T-cell proliferation, without inducing myelosuppression. It is a murine/human chimeric monoclonal antibody (IgG1κ).

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