Trihexyphenidyl

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Contents

Introduction

Clinical Use

Indications

Administration

Oral 1md od in adults up to 20mg in divided doses per day

Clinical Issues

Contra-indications

Cautions and Interactions

Side effects

  • Confusion and memory impairment (common)
  • Constipation
  • Dry mouth
  • Nausea and vomiting
  • Tachycardia
  • Dizziness
  • Hallucinations and euphoria
  • Anxiety and restlessness
  • Urinary retention
  • Acute angle glaucoma (rare)

Special advice

Try not to use in non drug induced progressive parkinsonism as CNS side-effects such as hallucinations and cognitive impairment tend to become problematical and withdrawal is difficult.

Pharmacology