Bicalutamide

From Ganfyd

rINN: Bicalutamide

Other Names

Casodex^®

Pharmacological Information

Pharmacology Images

Bicalutamide Molecule

Web information on Bicalutamide

NHS Evidence on Bicalutamide

DrugBank on Bicalutamide

Relevant Clinical Literature

Pubmed on Bicalutamide

RCT with Bicalutamide

Systematic reviews of Bicalutamide

Bicalutamide in N Eng J Med, Lancet, JAMA, BMJ

Bicalutamide in Cochrane Collaboration

TRIP Database on Bicalutamide

Google Scholar on Bicalutamide

Bandolier on Bicalutamide

UK Guidance

SNOMED search

Nice Guidance on Bicalutamide

BNF-registration required
BNF for children-registration required

UK directory of medicines

UK Medicine Guide (eg pictures of capsules)

Centre for Reviews and Dissemination databases -DARE & NHS EED (evaluates reliability of research)

Prodigy Guidance on Bicalutamide

Regulatory Literature

UK SPCs of medicines with marketing authorisation

EMEA search

FDA search

Other Literature

PubChem on Bicalutamide

CTD (Comparative Toxicogenomics Database) link

ChemIndustry.com link

Protein Structural Information

Biological Information (GenomeNet)

Protein Knowledgebase (UniProtKB)

Please read pharmacological data limitations

Other Wikis

Medpedia on Bicalutamide (Less technical, good quality control)

Wikipedia on Bicalutamide (Less technical, ? quality control)

Introduction

Anti-androgen

Clinical Use

Indications

• Carcinoma of prostate (Locally advanced) -no longer recommended in this indication (UK CSM)
• To reduce tumour flare with gonadorelin therapy

Administration

Oral

Clinical Issues

Contra-indications

Cautions and Interactions

Side effects

Special advice

Pharmacology