Brilacidin

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rINN: Brilacidin
Other Names
Brilacidin tetrahydrochloride, PMX-30063, N,N'-bis[3-{[5-(carbamimidoylamino)pentanoyl] amino} -2- [(3R)-pyrrolidin-3-yloxy]- 5-(trifluoromethyl) phenyl] pyrimidine- 4,6- dicarboxamide, Pyrimidinedicarboxamide,N4,N6 -bis [3- [ [5- [(aminoiminomethyl) amino]-1- oxopentyl]amino]-2- [(3 R)-3- pyrrolidinyloxy]-5-(trifluoromethyl) phenyl]-, hydrochloride (1:4)
Pharmacological Information
Pharmacology Images
File:BrilacidinMolecule.png
Brilacidin Molecule
Web information on Brilacidin
Relevant Clinical Literature
UK Guidance
Regulatory Literature
Other Literature
Other Wikis
Wikipedia on Brilacidin (Less technical, ? quality control)

Contents

Introduction

Brilacidin is an antibiotic being developed to treat bacterial skin infections and oral mucositis. It may offer short oral/topical courses directed at multi-drug resistant bacteria.

Clinical Use

Indications

Administration

Oral

Clinical Issues

Contra-indications

Cautions and Interactions

Side effects

Special advice

Pharmacology

A defensin-mimic peptide analogue that disrupts bacterial cell membranes.