Beta-type platelet-derived growth factor receptor

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Common Name:Beta-type platelet-derived growth factor receptor
Other Names, such as IUPAC Name
EC:2.7.10.1, PDGF receptor beta, PDGF-R-beta, CD140b
Biochemical Information
Molecular Structure
Important Issues in Man
Relevant Clinical Literature
UK Guidance
Other Wikis

Beta-type platelet-derived growth factor receptor (PDGF receptor beta) is coded by PDGFRB gene at 5q31-q32 and binds specifically to PDGFB and PDGFD with tyrosine-protein kinase activity. It is implicated in atherogenesis and in cell transformation by oncogenes. Gene mutations are associated with:

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