Capecitabine

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Contents

Introduction

An oral prodrug converted by 3 enzyme steps to fluorouracil (5-FU).

Clinical Use

Likely to be increasingly substituted for fluorouracil as the clinical trial data comes out[1][2].

Indications

May include:

  • Advanced gastric cancer.
  • Advanced (metastatic) colorectal cancer.
  • Advanced (metastatic) breast cancer.

Administration

oral

Clinical Issues

Contra-indications

Cautions and Interactions

Side effects

Special advice

Pharmacology

References