The vast majority of pancreatic cancers are adenocarcinomas. Most pancreatic adenocarcinomas are asymptomatic until too late for curative treatment. Prognosis is poor and palliative treatment challenging. Surgical treatment with curative intent carries significant morbidity and an appreciable mortality. For a review see:
- CT scan ideally with biopsy
- Staging laparoscopy
SurgicalIt is now known that if resection of a tumour of the pancreatic head causing jaundice is planned within 1 week of presentation, endoscopic preoperative biliary drainage should not be routine as it increases the complication rate
- Whipple's procedure
- Bypass procedure, e.g. gastrojejunostomy
- Palliative chemotherapy
Regimes include gemcitabine alone (approved by NICE in the UK ), and in combination with other drugs including erlotinib (Tarceva) and cisplatin.
- ↑ Yeo TP, Hruban RH, Leach SD, Wilentz RE, Sohn TA, Kern SE, Iacobuzio-Donahue CA, Maitra A, Goggins M, Canto MI, Abrams RA, Laheru D, Jaffee EM, Hidalgo M, Yeo CJ. Pancreatic cancer. Curr Probl Cancer. 2002 Jul-Aug ; 26(4): 176-275 available at 
- ↑ van der Gaag et al. Preoperative biliary drainage for cancer of the head of the pasncreas. N Eng J Med 2010;362;129-37
- ↑ 
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