Carnitine acylcarnitine translocase
Carnitine-acylcarnitine translocase (CAC, CACT, SLC25A20) is a mitochondrial-membrane carrier protein that shuttles carnitine between the cytosol and the intramitochondrial matrix. It is coded for at 3p21.31 and has highest activity in heart, skeletal muscle and liver.
Childhood primary carnitine-acylcarnitine translocase deficiency is well described.
Inhibitors include hydrazonopropionic acids which cause hypoglycaemia but presumably are toxic as none is in pharmacological development.