Category:Acetylcholinesterase inhibitors
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Web Resources for Acetylcholinesterase inhibitors
Relevant Clinical Literature
UK Guidance
Two sorts:-
Those used in anaesthetics to reverse neuromuscular blockade, and those intended to affect the central nervous system to improve mentation.
The latter are licensed for use in the treatment of mild to moderate Alzheimer's disease. In long term use they appear to have a limited, if any benefit, but some patients with various dementia presentations, not necessarily Alzheimer's disease do seem to have behavioural benefits in the short to medium term. Interestingly they may also improve memory in those with drug induced memory impairment such as found with cocaine[1] or cannabis[2]
References
- ↑ Mahoney JJ, Kalechstein AD, Verrico CD, Arnoudse NM, Shapiro BA, De La Garza R. Preliminary findings of the effects of rivastigmine, an acetylcholinesterase inhibitor, on working memory in cocaine-dependent volunteers. Progress in neuro-psychopharmacology & biological psychiatry. 2014 Apr 3; 50:137-42.(Link to article – subscription may be required.)
- ↑ Theunissen EL, Heckman P, de Sousa Fernandes Perna EB, Kuypers KP, Sambeth A, Blokland A, Prickaerts J, Toennes SW, Ramaekers JG. Rivastigmine but not vardenafil reverses cannabis-induced impairment of verbal memory in healthy humans. Psychopharmacology. 2015 Jan; 232(2):343-53.(Link to article – subscription may be required.)
Pages in category "Acetylcholinesterase inhibitors"
The following 7 pages are in this category, out of 7 total.
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NPR |
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