Entities in Class
Web Resources for Alkylating agents
Relevant Clinical Literature
Alkylate DNA so interfering with cell replication. So utilised to treat aggressively replicating malignancies on principle of differential toxicity to more leisurely normal cell replication.
- Sterility (males)
- Particularly acute non-lymphocytic leukaemia
- Nausea and vomiting
- Infections (secondary to neutropenia)