Category:Atypical antipsychotics
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Web Resources for Atypical antipsychotics
Relevant Clinical Literature
UK Guidance
A heterogeneous classification with marked overlap with the properties of first generation antipsychotics[1]
Contents |
Contra-indications
Dementia is probably a contraindication for any antipsychotic (fair evidence for increased mortality in long term use) and has an interesting medicolegal potential as it is unclear if following recent changes in datasheets (SPCs) and warnings from the regulatory authorities (eg FDA) any manufacturer will share liability for out of licence use (off license) use in newly commenced patients. In the UK an urgent review is taking place as of 2008.
Cautions
- Cardiovascular disease
- Epilepsy
- Elderly
- Dementia - increased risk stroke definite for olanzapine & risperidone
- Driving
- Withdrawal should be gradual
- Associated with increased venous thromboembolic disease
Side-effects
- Weight gain
- Parkinsonism
- Tardive dyskinesia
- Dizziness
- Postural hypotension
- Diabetes mellitus
- Neuroleptic malignant syndrome
References
- ↑ Leucht S, Corves C, Arbter D, Engel RR, Li C, Davis JM. Second-generation versus first-generation antipsychotic drugs for schizophrenia: a meta-analysis. Lancet. 2008 Dec 4.(Epub ahead of print) (Link to article – subscription may be required.)
>>Category:Atypical antipsychotics/Clinical issues
Pages in category "Atypical antipsychotics"
The following 11 pages are in this category, out of 11 total.
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