Long-acting β agonists mainly have a place as selective β2 agonists in inhalation therapy treating COPD or in combination therapy with steroids in unstable asthma. Use in unstable asthma as monotherapy is associated with increased mortality and morbidity.
- ↑ Walters EH, Gibson PG, Lasserson TJ, Walters JA. Long-acting beta2-agonists for chronic asthma in adults and children where background therapy contains varied or no inhaled corticosteroid. Cochrane database of systematic reviews (Online). 2007; (1):CD001385.(Epub) (Link to article – subscription may be required.)
- ↑ Liao MM, Ginde AA, Clark S, Camargo CA. Salmeterol use and risk of hospitalization among emergency department patients with acute asthma. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology. 2010 Jun; 104(6):478-84.(Link to article – subscription may be required.)