Inherited monoamine disorders have a wide impact, not just on individuals but also society, as they can modulate addictive behaviour and a large number of disease presentations. Acquired disorders affecting monoamines, include those related to substance abuse, changes in neuro-endocrine balance brought on by drugs and neuroendocrine tumours.
- The multiple associations of the SLC6A3 gene with:
- The dopa-responsive dystonias.
- Deficiency of aromatic amino acid decarboxylase (AADC gene defect) leads to a chronic and progressive neurological disorder with:
- Development delay
- Oculogyric crisis
- Vegetative symptoms
Some of these conditions have specific, perhaps curative treatment if offered early enough with easy to obtain drugs as is the case with the severe infantile parkinsonism caused by deficits in the SLC18A2 gene.
Pages in category "Monoamine disorders"
The following 20 pages are in this category, out of 20 total.