Chikungunya virus (CHIKV) is most likely of African origin. It was first isolated in Tanzania in 1953. The viral vector has a positive-stranded RNA genome and when transmitted to man by an Aedes mosquito causes Chickungunya fever which has a high and prolonged morbidity but a relatively low mortality. Genetic mutation of the viral genome is associated with outbreaks
- ↑ ROSS RW. The Newala epidemic. III. The virus: isolation, pathogenic properties and relationship to the epidemic. The Journal of hygiene. 1956 Jun; 54(2):177-91.
- ↑ Parola P, de Lamballerie X, Jourdan J, Rovery C, Vaillant V, Minodier P, Brouqui P, Flahault A, Raoult D, Charrel RN. Novel chikungunya virus variant in travelers returning from Indian Ocean islands. Emerg Infect Dis. 2006;12(10):1493-9.