Cholesteryl ester transfer protein

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Common Name:Cholesteryl ester transfer protein
Biochemical Information
Molecular Structure
Important Issues in Man
CETP inhibitors have failed to show net benefit in man
Relevant Clinical Literature
UK Guidance
Other Wikis
Wikipedia on Cholesteryl ester transfer protein (Less technical, ? quality control)

Cholesteryl ester transfer protein (CETP) transfers neutral lipid triglycerides and phospholipids for cholesteryl esters between lipoproteins (heteroexchange). Its role is influenced by lipid transfer inhibitor protein (LTIP) activity and the balance of activities may be very important in vivo, with some evidence that LTIP is more important as a regulator of HDL metabolism, and even permissive on CETP[1].