Churg-Strauss syndrome
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Medpedia on Churg-Strauss syndrome (Less technical, good quality control)
Wikipedia on Churg-Strauss syndrome (Less technical, ? quality control)
Churg-Strauss syndrome(Allergic granulomatosis angiitis) is a vasculitis of small to medium sized blood vessels characterised by:
- Eosinophilia
- Asthma
 | Described by the Mount Sinai Hospital (New York) pathologists Jacob Churg and Lotte Strauss in 1951. |
Contents |
Prodromal (Allergic) Phase
- Asthma (late onset)
- Sinusitis
- Nasal polyps
- Allergic rhinitis
- Recurrent pneumonia and/or bronchitis
- Typically lasts 3 months to 2 years
Hypereosinophilic Phase
- Chronic eosinophilic pneumonia
- Eosinophilic gastroenteritis
- Eosinophilia in blood is usual allowing clinical suspicion
- Lasts months or years and with treatment may never progress to
Systemic Vasculitis Phase
- Systemic symptoms
- Respiratory tract and gastrointestinal disease worsen
- Cardiac involvement
- Cutaneous vasculitis
- Neuropathies, rarely optic nerve involvement
- Arthritis
- Very rarely glomerulonephritis
