Ciclosporin

From Ganfyd

Jump to: navigation, search

Ciclosporin is widely used in transplantation and for immunomodulation in auto-immune diseases. It may have a role in minimising myocardial reperfusion injury through its actions on the mitochondrial inner membrane pore complex. Some of its functions might be better characterised as inhibition of programmed necroptosis.

Dosage

Requires full understanding of indication and renal function. Drug levels may need to be used.