Cirrhosis
From Ganfyd
Web Resources for Cirrhosis
Relevant Clinical Literature
RCT with Cirrhosis from Pubmed
UK Guidance
Other Wikis
Medpedia on Cirrhosis (Less technical, good quality control)
Wikipedia on Cirrhosis (Less technical, ? quality control)
Cirrhosis is fibrogen scarring of the liver as a result of a chronic hepatotoxic process. Replacement of hepatocytes with fibrous scarring reduces the functional capacity of the liver, in particular its role in synthesis and elimination. Liver function is also adversely affected by the loss of the normal liver architecture and may lead to portal hypertension.
Strictly speaking, cirrhosis is a histological diagnosis, after examining liver biopsy specimens.
Causes
- Chronic viral hepatitides - B (+/- D) and C
- Alcohol hepatitis
- Autoimmune hepatitis
- Primary sclerosing cholangitis
- Primary biliary cirrhosis
- Wilson's disease
- Haemochromatosis
- Alpha1-antitrypsin deficiency
- Non-alcoholic steatohepatitis
This article is a stub. Please feel free to expand it and make it more encyclopaedic.
