Clavulanic acid

From Ganfyd

rINN: Clavulanic acid

Pharmacological Information

Pharmacology Images

Clavulanic acid Molecule

Web information on Clavulanic acid

NHS Evidence on Clavulanic acid

DrugBank on Clavulanic acid

Other Issues for Clavulanic acid

Cholestatic jaundice is possibly associated

Relevant Clinical Literature

Pubmed on Clavulanic acid

RCT with Clavulanic acid

Systematic reviews of Clavulanic acid

Clavulanic acid in N Eng J Med, Lancet, JAMA, BMJ

Clavulanic acid in Cochrane Collaboration

TRIP Database on Clavulanic acid

Google Scholar on Clavulanic acid

Bandolier on Clavulanic acid

UK Guidance

SNOMED search

Nice Guidance on Clavulanic acid

BNF-registration required
BNF for children-registration required

UK directory of medicines

UK Medicine Guide (eg pictures of capsules)

Centre for Reviews and Dissemination databases -DARE & NHS EED (evaluates reliability of research)

Prodigy Guidance on Clavulanic acid

Regulatory Literature

UK SPCs of medicines with marketing authorisation

EMEA search

FDA search

Other Literature

PubChem on Clavulanic acid

CTD (Comparative Toxicogenomics Database) link

ChemIndustry.com link

Protein Structural Information

Biological Information (GenomeNet)

Protein Knowledgebase (UniProtKB)

Please read pharmacological data limitations

Other Wikis

Medpedia on Clavulanic acid (Less technical, good quality control)

Wikipedia on Clavulanic acid (Less technical, ? quality control)

Introduction

Clavulanic acid is a beta-lactamase inhibitor often added penicillins to extend the spectrum, e.g. co-amoxiclav is a combination of amoxicillin and clavulanic acid. Another combination is that with ticarcillin (Timentin^®)

Clinical Use

Indications

Administration

Oral

IV

Clinical Issues

Contra-indications

Cautions and Interactions

Side effects

Special advice

Pharmacology