Coenzyme Q10

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Coenzyme Q 10 (also known as Ubiquinone, although actually it is one of many ubiquinones) is a naturally occurring enzyme cofactor found in mitochondria. It can be obtained from diet or food supplements although it is also produced endogenously. The body uses it to promote cell growth and to protect cells from damage that could lead to cancer. It can be depleted by statins. Stopping the statin solves the problem with a normal diet and metabolism, although clinical trials suggest it might have a role if the statin is to be continued in those with muscle pain[1]. As of 2007 Bandolier has summarised for convenience the evidence base for use in hypertension[2], migraine[3]. and statin myopathy[4] and notes the absence of registered clinical trials likely to tell us more in the near future. Its only definite indication is where a patient has one of the at least five known phenotypes associated with the rare autosomal recessive CoQ deficiency.

A large health food fad based on this exists.

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