Collagenase clostridium histolyticum

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rINN: Collagenase clostridium histolyticum
Other Names
Xiaflex®
Pharmacological Information
Web information on Collagenase clostridium histolyticum
Relevant Clinical Literature
UK Guidance
Regulatory Literature
Other Literature
Other Wikis
Wikipedia on Collagenase clostridium histolyticum (Less technical, ? quality control)

Contents

Introduction

It is being developed for use in Dupuytren's disease and is expected to get rapid marketing authorisation after publication of a landmark trial[1]

Clinical Use

Clinical Issues

Tendon rupture can occur in about 1 in 100 and complex regional pain syndrome may also occur

Contra-indications

  • Allergy to the product

Cautions and Interactions

Side effects

  • Localized swelling
  • Pain
  • Bruising
  • Pruritus
  • Transient regional lymph-node enlargement and tenderness

Special advice

Pharmacology

References

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