Colorectal cancer/Staging

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Colorectal Cancer Staging
Classification In situ Stage I/A Stage II/B Stage III/C Stage IV/D Comments
TNM Tis N0 M0 I: T1 N0 M0
T2 N0 M0
IIA: T3 N0 M0
IIB: T4 N0 M0
IIIA: T1/2 N1 M0
IIIB: T3/4 N1 M0
IIIA: Tany N2 M0
IV: Tany Nany M1
Dukes' staging A: No breach of muscularis propria B: Breach of muscularis propria C: LN metastases n.a.
Modified Dukes' A:Limited to mucosa B1: Invasion of submucosa, but not beyond muscularis
C1:Regional lymph node spread
C2: Regional LN and apical LN +ve
D: Distant metastases
Astler-Coller A: No breach of muscularis propria B: Invasion of submucosa or muscularis propria C1/2: As B, but with LN involvement n.a.
Modified Astler-Coller A:Limited to mucosa B1: Invasion of submucosa, but not beyond muscularis
B2: Through muscularis
B3: Adherent or invading adjacent organs.
C1-3: As B, but with LN involvement n.a.
AJCC stage A: Invasion to submucosa B1: invasion, but not through muscularis propria
B2: invasion through muscularis
B3: equiv. to T4 in TNM
C1-C3: equivalent to corresponding grade B, but with LN involvement D: Distant metastases 100