Congo Red staining
Diazo chemical. Used primarily in the staining of amyloid. Materials that an affinity for Congo Red (CR) are known as congophilic.
The most well known congophilic material is amyloid and also shows birefringence under polarising light, typically 'apple green', but other colours may be seen. CR also avidly stains eosinophils. Depending on the exact method of staining, collagen and elastic fibres may also stain positively.
- ↑ Steensma DP. "Congo" red: out of Africa? Archives of pathology & laboratory medicine. 2001 Feb; 125(2):250-2.(<0250:CR>2.0.CO;2 Link to article – subscription may be required.)
- ↑ Howie AJ, Brewer DB, Howell D, Jones AP. Physical basis of colors seen in Congo red-stained amyloid in polarized light. Laboratory investigation; a journal of technical methods and pathology. 2008 Mar; 88(3):232-42.(Link to article – subscription may be required.)
- ↑ Elghetany MT, Saleem A, Barr K. The congo red stain revisited. Annals of clinical and laboratory science. 1989 May-Jun; 19(3):190-5.