Conivaptan

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Contents

Introduction

A non-selective angine-vasopressin receptor antagonist (vaptan). Unclear if works in heart failure like more selective agents, as worsening heart failure has been reported[1].

Clinical Use

Indications

  • (FDA) Euvolaemic or hypervolaemic hyponatraemia [2] (secondary to syndrome of inappropriate antidiuretic hormone secretion theoretically but indication stretch seems likely[3]).

Administration

IV

Clinical Issues

Contra-indications

Cautions and Interactions

Side effects

Special advice

Pharmacology

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