Cord colitis syndrome
Cord colitis syndrome (CCS) is a form of colopathy, typically associated with diarrhoeal symptoms, occurring after haematopoietic stem cell transplantation using umbilical cord stem cells. The pathogenesis is not entirely clear. Bradyrhizobium bacteria have been implicated, but this may represent contamination. The symptoms may be indistinguishable from graft-versus-host disease (GvHD). Distinguishing between the two entities is important because CCS is treated with antibiotics, while GvHD is treated with increased immunosuppression.