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A fungal disease caused by either Cryptococcus neoformans or Cryptococcus gattii[1] in man, classic manifest as respiratory pneumonia following inhalation from the environment of spores. Its activation in AIDS and other immuno-suppressive illnesses is now well known. However it can affect the immuno-competent and is a common infection in other animals.

As well as pulmonary cryptococcosis, cutaneous cryptococcosis[2], osseous cryptococcosis[3] and cryptococcal meningitis[4] are well described.


The current standard of care is amphotericin B and flucytosine. However fluconazole can be substituted for the later. Other drugs such as isavuconazole may be appropriate..


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