Cyproterone

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rINN: Cyproterone
Other Names
Cyproterone acetate,Cyprostat ®,Androcur®
Pharmacological Information
Pharmacology Images
Cyproterone Molecule
Cyproterone.png
Web information on Cyproterone
NHS Evidence on Cyproterone
DrugBank on Cyproterone
Relevant Clinical Literature
Pubmed on Cyproterone
RCT with Cyproterone
Systematic reviews of Cyproterone
Cyproterone in N Eng J Med, Lancet, JAMA, BMJ
Cyproterone in Cochrane Collaboration
TRIP Database on Cyproterone
Google Scholar on Cyproterone
Bandolier on Cyproterone
UK Guidance
Nice Guidance on Cyproterone

BNF-registration required
BNF for children-registration required

UK directory of medicines
UK Medicine Guide (eg pictures of capsules)
Centre for Reviews and Dissemination databases -DARE & NHS EED (evaluates reliability of research)
Prodigy Guidance on Cyproterone
Regulatory Literature
UK SPCs of medicines with marketing authorisation
EMEA search
FDA search
Other Literature
PubChem on Cyproterone
CTD (Comparative Toxicogenomics Database) link
ChemIndustry.com link
Protein Structural Information
Biological Information (GenomeNet)
Protein Knowledgebase (UniProtKB)
Please read pharmacological data limitations
Other Wikis
Medpedia on Cyproterone (Less technical, good quality control)
Wikipedia on Cyproterone (Less technical, ? quality control)

Cyproterone acetate is used to treat:

Contents

Clinical Issues

Contra-indications

Cautions and Interactions

  • Dose dependent hepatotoxicity (above about 200mg daily)

Side effects

  • Induction of meningioma
  • Breathlessness
  • Adrenocortical suppression
  • Hypochromic anaemia
  • Inhibition of sexual drive and potency
  • Inhibition of spermatogenesis
  • Gynaecomastia

Special advice

Pharmacology

Highly bioavailable.

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