Cytarabine

From Ganfyd

rINN: Cytarabine

Other Names

Ara-C, cytosine arabinoside, 4-amino-1-[(2R,3S,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl] pyrimidin-2-one, Cytosar-U®, Tarabine PFS®, Depocyt®

Pharmacological Information

Pharmacology Images

Cytarabine Molecule

Web information on Cytarabine

NHS Evidence on Cytarabine

DrugBank on Cytarabine

Relevant Clinical Literature

Pubmed on Cytarabine

RCT with Cytarabine

Systematic reviews of Cytarabine

Cytarabine in N Eng J Med, Lancet, JAMA, BMJ

Cytarabine in Cochrane Collaboration

TRIP Database on Cytarabine

Google Scholar on Cytarabine

Bandolier on Cytarabine

UK Guidance

SNOMED search

Nice Guidance on Cytarabine

BNF-registration required
BNF for children-registration required

UK directory of medicines

UK Medicine Guide (eg pictures of capsules)

Centre for Reviews and Dissemination databases -DARE & NHS EED (evaluates reliability of research)

Prodigy Guidance on Cytarabine

Regulatory Literature

UK SPCs of medicines with marketing authorisation

EMEA search

FDA search

Other Literature

PubChem on Cytarabine

CTD (Comparative Toxicogenomics Database) link

ChemIndustry.com link

Protein Structural Information

Biological Information (GenomeNet)

Protein Knowledgebase (UniProtKB)

Please read pharmacological data limitations

Other Wikis

Medpedia on Cytarabine (Less technical, good quality control)

Wikipedia on Cytarabine (Less technical, ? quality control)

Nucleoside consisting of the pyrimidine cytosine but, unlike cytidine which has a deoxyribose sugar, cytarabine has an arabinose sugar. Used as an anti-metabolite/chemotherapeutic drug in the treatment of haematological malignancies. It also has anti-viral properties.