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A peptide derived from activity-dependent neuroprotective protein which is in development for treatment of progressive supranuclear palsy and possibly other neurodegenerative disorders or even immune disorders such as multiple sclerosis. As it provides protection against kainic acid excitotoxicity in hippocampal neuronal cultures it s also being examined as a neuroprotective agent in epilepsy. It prevents microtubule degradation under oxidative stress and may inhibit the early events of apoptosis. It binds to tubulin.