The prototype polychlorinated biphenyl and like the others a rather nasty biological and environmental toxin which can be produced by incomplete combustion. Toxicity of the class is measured in Toxic Equivalency Factors (TEFs).
- Cognitive impairment (including from in utero exposure)
- Cancer induction
- Hormone abnormalities
- Multiple cellular process poisoning (acute exposure)
According to a ProMED moderator, citing a paper by Bertazzi et al, , "Although there seems to be no doubt in the lay press about dioxin's status as a carcinogen, there seems to be some controversy in the toxicology literature."
- Wikipedia Dioxin page
- Committee on toxicity of chemicals in food, consumer products and the environment (COT) Lay summary of the cot statement on the tolerable daily intake for dioxins and dioxin-like polychlorinated biphenyls: Dioxins and dioxin-like PCBs – How the tolerable daily intake (TDI) was set See also full statement and other COT statements on dioxins.
- UK's HPA web site
- Food Standards Agency of Ireland website
- WHO's Fact sheet N225 "Dioxins and their effects on human health," updated November 2007
- ↑ Boersma ER, Lanting CI. Environmental exposure to polychlorinated biphenyls (PCBs) and dioxins. Consequences for longterm neurological and cognitive development of the child lactation. Advances in experimental medicine and biology. 2000; 478:271-87.
- ↑ Bertazzi PA, Bernucci I, Brambilla G, Consonni D, Pesatori AC. The Seveso studies on early and long-term effects of dioxin exposure: a review. Environmental health perspectives. 1998 Apr; 106 Suppl 2:625-33.
- ↑ ProMED-Mail. Dioxin contamination, pig meat - Ireland, Europe. 2008 (7 November); Accessed: 2008 (8 November). Archive Ref No: 20081207.3842
- ↑ Committee on toxicity of chemicals in food, consumer products and the environment. Lay summary of the COT statement on the tolerable daily intake for dioxins and dioxin-like polychlorinated biphenyls: Dioxins and dioxin-like PCBs – How the tolerable daily intake (TDI) was set. >?2001