Dual specificity tyrosine-phosphorylation-regulated kinase 1A

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Common Name:Dual specificity tyrosine-phosphorylation-regulated kinase 1A
Other Names, such as IUPAC Name
DYRK1A, dual-specificity tyrosine phosphorylation-regulated kinase, DYRK1, DYRK, EC 2.7.12.1, Protein kinase minibrain homolog, MNBH, hMNB, HP86, dual specificity YAK1-related kinase
Biochemical Information
Molecular Structure
Important Issues in Man
Relevant Clinical Literature
UK Guidance
Other Wikis

Dual specificity tyrosine-phosphorylation-regulated kinase 1A is the protein kinase coded by the DYRK1A gene at 21q22.1 whose excessive function acting on the gene REST is believed to be a key element in the clinical phenotype of Down syndrome.