EBV positive mucocutaneous ulcer

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A lymphoproliferative conditions resulting in skin or mucosal ulceration. Both its clinical and histological appearances can appear malignant, but it runs a benign course. It is EBV-driven, due to iatrogenic immunosuppression or age-related immunosenesence. It typically resolves with reduction or withdrawal of immunosuppression (in iatrogenic cases). Spontaneous resolution is described in some cases within the 'age-related' group (9 out of 17 cases in the original series).[1][2]