EBV positive mucocutaneous ulcer
A lymphoproliferative conditions resulting in skin or mucosal ulceration. Both its clinical and histological appearances can appear malignant, but it runs a benign course. It is EBV-driven, due to iatrogenic immunosuppression or age-related immunosenesence. It typically resolves with reduction or withdrawal of immunosuppression (in iatrogenic cases). Spontaneous resolution is described in some cases within the 'age-related' group (9 out of 17 cases in the original series).
- ↑ Dojcinov SD, Venkataraman G, Raffeld M, Pittaluga S, Jaffe ES. EBV positive mucocutaneous ulcer--a study of 26 cases associated with various sources of immunosuppression. The American journal of surgical pathology. 2010 Mar; 34(3):405-17.(Link to article – subscription may be required.)
- ↑ Dojcinov SD, Venkataraman G, Pittaluga S, Wlodarska I, Schrager JA, Raffeld M, Hills RK, Jaffe ES. Age-related EBV-associated lymphoproliferative disorders in the Western population: a spectrum of reactive lymphoid hyperplasia and lymphoma. Blood. 2011 May 5; 117(18):4726-35.(Link to article – subscription may be required.)