- Molecular Weight: 160,000
- Normal plasma concentration 5 μg/ml
- 20-30% of normal concentration required for haemostasis
Important Issues in Man
Relevant Clinical Literature
Medpedia on Factor XI (Less technical, good quality control)
Wikipedia on Factor XI (Less technical, ? quality control)
‘’’Factor XI’’’ circulates in plasma as a noncovalent complex with H-kininogen (HK), Once bound to the platelet surface, factor XI is efficiently activated to factor XIa by coagulation proteases such as thrombin and activated factor XII.