- Molecular Weight: 320,000
- Normal plasma concentration 30 μg/ml
- 1-5% of normal concentration required for haemostasis
The last major component of the coagulation and fibrinolysis pathway which stabilises clots. It is a tetramer of two A chains and two B chains found in both plasma but also most cell cyrtoplasm. The A chain, factor XIIIA catalyzes the formation of gamma-glutamyl-epsilon-lysine cross-links between fibrin chains.