Fibroblast growth factor receptor 3

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Common Name:Fibroblast growth factor receptor 3
Other Names, such as IUPAC Name
FGFR-3,, CD333
Biochemical Information
Molecular Structure
Important Issues in Man
Relevant Clinical Literature
UK Guidance
Other Wikis
Wikipedia on Fibroblast growth factor receptor 3 (Less technical, ? quality control)

The gene FGFR3 (JTK4) at 4p16.3 codes for a 806 amino-acid pro-peptide which is processed to fibroblast growth factor receptor 3 a tyrosine kinase receptor protein with several isoforms. Defects are associated with various forms of skeletal maldevelopment including:[1]

Abnormalities in the gene are also associated with multiple myeloma, seborrheic keratoses, bladder and cervical cancer.


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