Follicle-stimulating hormone
From Ganfyd
rINN: Follicle-stimulating hormone
Other Names
follitropin alfa, GONAL-f®
Pharmacological Information
Pharmacology Images
File:Follicle-stimulating hormoneMolecule.png
Follicle-stimulating hormone Molecule
Web information on Follicle-stimulating hormone
Relevant Clinical Literature
UK Guidance
Regulatory Literature
Other Literature
Please read pharmacological data limitations
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Medpedia on Follicle-stimulating hormone (Less technical, good quality control)
Wikipedia on Follicle-stimulating hormone (Less technical, ? quality control)
Common Name:Follicle-stimulating hormone
Alternative Name:follitropin alfa
Biochemical Information
Molecular Structure
Important Issues in Man
Relevant Clinical Literature
UK Guidance
Other Wikis
Medpedia on Follicle-stimulating hormone (Less technical, good quality control)
Wikipedia on Follicle-stimulating hormone (Less technical, ? quality control)
Contents |
Introduction
Heterodimer of glycoprotein hormones alpha chain and follitropin subunit beta. Levels are raised in primary gonadal failure and after menopause.
Clinical Use
Diagnosis of gonadal failure and treatment of infertility
Indications
- Anovulation (including polycystic ovary syndrome) in women unresponsive to clomiphene.
- Stimulated in vitro fertilisation (IVF), gamete intra-fallopian transfer (GIFT) and zygote intra-fallopian transfer (ZIFT).
- In association with a luteinizing hormone (LH) preparation (eg follitropin alfa/lutropin alfa for stimulation of follicular development in women with severe LH and FSH deficiency.
- Stimulation of spermatogenesis in men who have congenital or acquired hypogonadotrophic hypogonadism with concomitant human chorionic gonadotrophin .
Administration
IV as 87 µgrams delivering 77 µgrams, equivalent to 1050 IU
