A medical device developed to reduce wound infection and widely used in surgery as a result of several open and small randomised trials until a randomized controlled trial showed in 2010 that if wetted and used in colorectal surgery it paradoxically produced significantly more surgical-site infections. It also has no advantage in treating pilonidal sinus and sternotomy wounds. It may be effective in initially dry wounds with good haemostasis but this should be shown in properly powered studies.
- ↑ de Bruin AF, Gosselink MP, Rutten HJ. Gentamicin Sponge for Infection Prophylaxis in Colorectal Surgery. The New England journal of medicine. 2010 Dec 23; 363(26):2566-2567.(Link to article – subscription may be required.)
- ↑ Bennett-Guerrero E, Pappas TN, Koltun WA, Fleshman JW, Lin M, Garg J, Mark DB, Marcet JE, Remzi FH, George VV, Newland K, Corey GR. Gentamicin-collagen sponge for infection prophylaxis in colorectal surgery. The New England journal of medicine. 2010 Sep 9; 363(11):1038-49.(Link to article – subscription may be required.)
- ↑ Andersson RE, Lukas G, Skullman S, Hugander A. Local administration of antibiotics by gentamicin-collagen sponge does not improve wound healing or reduce recurrence rate after pilonidal excision with primary suture: a prospective randomized controlled trial. World journal of surgery. 2010 Dec; 34(12):3042-8.(Link to article – subscription may be required.)
- ↑ Bennett-Guerrero E, Ferguson TB, Lin M, Garg J, Mark DB, Scavo VA, Kouchoukos N, Richardson JB, Pridgen RL, Corey GR. Effect of an implantable gentamicin-collagen sponge on sternal wound infections following cardiac surgery: a randomized trial. JAMA : the journal of the American Medical Association. 2010 Aug 18; 304(7):755-62.(Link to article – subscription may be required.)