Gentamicin–collagen sponge

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A medical device developed to reduce wound infection and widely used in surgery as a result of several open and small randomised trials[1] until a randomized controlled trial showed in 2010 that if wetted and used in colorectal surgery it paradoxically produced significantly more surgical-site infections[2]. It also has no advantage in treating pilonidal sinus[3] and sternotomy wounds[4]. It may be effective in initially dry wounds with good haemostasis but this should be shown in properly powered studies.

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