Gluten ataxia

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Gluten ataxia is a form of autoimmune cerebellar ataxia associated with high titres of gliadin antibodies. While well described in coeliac disease it is usually independent of this[1] so is problematically harder to diagnose given move to more specific antibodies in coeliac disease. A homology between the 33-mer gliadin peptide and protein lifeguard 1, a component of the NMDA glutamate receptor ion channel has recently been postulated as an explanation for this and several other associations of coeliac disease[2]

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