Histopathology of the appendix

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Site of inflammation and occasionally tumours.

Incidental neuroendocrine tumours ('carcinoid'), is rare at <1% (5/1237,[1] 20/1350,[2] and 7/1485.[3]), but when found, is commonly at the tip. If at the tip and less than 1-2cm, further intervention is usually not required. There is uncertainty over the indications for a right hemicolectomy, but these may include:[4]

  • large tumours (>2cm)
  • tumours at the base
  • invasion into the mesoappendix
  • high-grade histological features
  • goblet adenocarcinoid sub-type