Hypertrophic pulmonary osteoarthropathy

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Hypertrophic pulmonary osteoarthropathy is the combination of finger clubbing with the joint symptoms of arthralgia, swelling and stiffness affecting mainly the fingers, wrists, ankles, and knees[1]. It was first described by Bamberger in association with tuberculosis[2] and Saundby in association with lung malignancy[3], although the term was invented the next year by Marie[4].


  1. Yacoub MH. Relation between the histology of bronchial carcinoma and hypertrophic pulmonary osteoarthropathy. Thorax 1965:20:537. doi: 10.1136/thx.20.6.537
  2. Bamberger E. Sitzung der K. K. Ges. der Aerzte in Wien 8 Marz 1889. Wien. klin. Wschr.:2;226.
  3. Saundby R. A case of acromegaly. Illustrated med. News 1889:2;195.
  4. Marie P. De l'osteo-arthropathie hypertrophiante pneumique. Rev. Mgd. (Paris) 1890:10;1.