Imipramine

From Ganfyd

Jump to: navigation, search

Contents

Introduction

Imipramine was discovered by serendipity to act in depression[1][2] and thus was the first tricyclic antidepressant. It had been developed as part of a search for drugs useful in the treatment of schizophrenia. It was later demonstrated to be effective in panic attacks[3].

Clinical Use

Indications

  • Depression

Administration

Oral

Clinical Issues

  • Not recommended for former indication of urinary incontinence due to poor relative evidence base

Contra-indications

Cautions and Interactions

Side effects

Special advice

Pharmacology

References

Personal tools