- Human normal immunoglobulin
- Octagam® - Suspended in EU due to thromboembolic events September 2010
- Hepatitis B immunoglobulin
- Hepatect CP®
- Rhesus D immunoglobulin
- Rabbit anti-human thymocyte immunoglobulin
- Blood products containing antibodies.
Immunoglobulin (commonly referred to as "human normal immunoglobulin" or "HNIG") is occasionally used to protect vulnerable individuals (by providing "passive immunity") against certain infectious diseases. In England, immunoglobulin can be obtained from or via the Health Protection Agency - see their Immunoglobulin Handbook page.
Human normal immunoglobulin (HNIG) is prepared from pooled donations and may be used to protect susceptible contacts against common viruses such as hepatitis A, measles, mumps and rarely rubella. There is the potential for biological contamination or as with Octagam® in 2010 where thromboembolic reactions occurred, unexpected events probably related to processing affecting other plasma proteins.
HBIG is used to protect an individual exposed to the Hepatitis B.
Usually administered around the cleaned wound followed by vaccination.
Anti-sera exists but is likely to easily obtainable only for endemic species.
Designed to target Rhesus D positive erythrocytes than may be transferred from a baby to its Rhesus negative mother during pregnancy. The Anti-D immunoglobulin targets and neutralises the Rhesus D antigen. This prevents the mother's immune system from encountering the antigen and protects any further Rhesus positive babies that the mother may have.
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