Inotrope

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An inotrope is agent that affects the force of the contractility of the heart. The term is used mostly for positive inotropes which increase the force of contraction. Negative inotropes also exist. Very few inotropic drugs are pure inotropes; many also have effects on the heart rate (chronotropes) and the systemic vascular resistance (vasopressors/vasodilators). Although the term 'inotrope' is often loosely used to refer to any drug with a combination of the above effects, the term vasoactive drug is a more accurate description.

Most inotropes exert their effects through stimulation of beta-1 adreno-receptors and are a subgroup of the sympathomimetic drugs

Common inotropes in use include:

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